Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor.
CAS:106941-25-7
分子式:C8H12N5O4P
分子量:273.2
纯度:98%
存储:Store at -20°C
Background:
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. When evaluated in animal and clinical models of infections, its antiviral spectrum was shown to uniquely encompass activity against herpes viruses (HSV-1, HSV-2, VZV, CMV, EBV, HHV-6, HHV-7, and HHV-8), hepatitis B virus (HBV), and HIV (HIV-1, HIV-2, SIV, and FIV). Adefovir-associated resistance mutations have not yet been observed in HBV resistance surveillance clinical studies.