BI-1347 是一种有效的 CDK8 抑制剂,IC50 值为 1.1 nM,详细信息请参考 WO2017202719A1 中的产物 I-003。
CAS:2163056-91-3
分子式:C22H20N4O
分子量:356.42
纯度:98%
存储:Store at -20°C
Background:
BI-1347 is a potent CDK8 inhibitor extracted from patent WO2017202719A1, product I-003, has an IC50 of 1.1 nM[1].
CDK8|1.1 nM (IC50)
[1]. Harald Engelhardt, et al. New phenylpyrazolylacetamide compounds and derivatives as cdk8/cdk19 inhibitors.