BMS-818251 is a highy potent hiv-1 entry inhibitor, targeting the gp120 subunit of the hiv-1 envelope (env) trimer, interacting with gp120 residues from the conserved β20-β21 hairpin References: Lai YT, Wang T, O'Dell S, Louder MK, Schon A, Cheung CSF, Chuang GY, Druz A, Lin B, McKee K, Peng D, Yang Y, Zhang B, Herschhorn A, Sodroski J, Bailer RT, Doria-Rose NA, Mascola JR, Langley DR, Kwong PD. Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry. Nat Commun. 2019 Jan 3;10(1):47. doi: 10.1038/s41467-018-07851-1. PubMed PMID: 30604750; PubMed Central PMCID: PMC6318274.
纯度:≥98%