β-AminoAcidImagabalinHydrochloride(PD-0332334)是电压依赖性钙离子(calciumchannel)通道的α2δ亚基的配体
CAS:610300-00-0
分子式:C9H20ClNO2
分子量:209.71
纯度:98%
存储:Store at -20°C
Background:
β-Amino Acid Imagabalin Hydrochloride (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel.
β-Amino Acid Imagabalin Hydrochloride had been in phase III clinical trials for the treatment of generalised anxiety disorders. However, this research has been discontinued[2]. β-Amino Acid Imagabalin Hydrochloride had been also in phase I clinical trials for the treatment of chronic kidney disease[3].
[1]. Birch M, et al. A Simplified Process for the Manufacture of Imagabalin Hydrochloride (PD-0332334), an α2δ-Ligand for the Treatment of Generalised Anxiety Disorder. Org. Process Res. Dev., 2011, 15 (6), pp 1358-1364