(±)-2-propyl-4-Pentenoic acid (4-ene VPA) is a major metabolite of valproic acid .
CAS:1575-72-0
分子式:C8H14O2
分子量:142.2
纯度:98%
存储:Store at -20°C
Background:
(±)-2-propyl-4-Pentenoic acid (4-ene VPA) is a major metabolite of valproic acid . It undergoes β-oxidation to form reactive metabolites that induce hepatotoxicity in rats. 4-ene VPA is also neuroteratogenic, reducing forebrain size and inducing deformation of the neural tube in mouse embryos.