Stearoylethanolamide是一种具有促细胞凋亡活性的内源性大麻素类化合物。
CAS:111-57-9
分子式:C20H41NO2
分子量:327.55
纯度:98%
存储:Store at -20°C
Background:
Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.
Stearoylethanolamide (SEA) is present in human, rat and mouse brain in amounts comparable with those of the endocannabinoid anandamide (arachidonoylethanolamide; AEA). Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity, which is regulated by NO in a way opposite to that reported for AEA[1].
[1]. Maccarrone M, et al. Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem J. 2002 Aug 15;366(Pt 1):137-44.