HDAC-IN-4 is a histone deacetylase (HDAC) inhibitor, extracted from patent WO/2007045844 A1 20070426.
CAS:934828-12-3
分子式:C24H29N5O
分子量:403.52
纯度:98%
存储:Store at -20°C
Background:
CXD101 is a class I-selective HDAC inhibitor (HDAC1 (IC50, 63 nM), HDAC2 (IC50, 570 nM), HDAC3 (IC50, 550 nM). CXD101 has no activity against HDAC class II[1].
参考文献:
[1]. Eyre TA, et al. Predictive biomarkers for disease sensitivity in lymphoma - the holy grail for HDAC inhibitors Oncotarget. 2018 Dec 18;9(99):37280-37281.