antagonist of muscarinic M2 and M3 receptor
CAS:3254-89-5
分子式:C21H28ClNO
分子量:345.91
纯度:98%
存储:Store at -20°C
Background:
Diphenidol hydrochloride is a muscarinic antagonist employed as an antiemetic and as an antivertigo agent.
参考文献:
[1]. Leung YM, et al. Inhibition of voltage-gated K+ channels and Ca2+ channels by diphenidol. Pharmacol Rep. 2012;64(3):739-44.
[2]. Leung YM, et al. Diphenidol inhibited sodium currents and produced spinal anesthesia. Neuropharmacology. 2010 Jun;58(7):1147-52.
[3]. Andersson M, et al. Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder. Auton Neurosci. 2012 Sep 25;170(1-2):5-11.