E3LigaseLigand-LinkerConjugates20由降解决定子和PROTAC连接物组成(参考文献中的化合物DL7-TL)。
CAS：1950635-15-0
分子式：C23H30N4O6
分子量：458.51
纯度：98%
存储：Store at -20°C

Background:

E3 Ligase Ligand-Linker Conjugates 20 is a degron-linker (refer to Compound DL7-TL). The PROTAC linker is bound lo at least one targeting ligand.

Degron-linker-targeting ligand, wherein the linker is covalently bound lo at least one degron and at least one targeting ligand, the degron is a compound capable of binding to an ubiquitin ligase such as an E3 ubiquitin ligase (e g, cereblon), and the targeting ligand is capable of binding to the targeted protein (s)[1].

[1]. James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.