NRC-2694是一种表皮生长因子受体(EGFR)拮抗剂，具有抗癌、抗增殖的活性。
CAS：936446-61-6
分子式：C24H26N4O3
分子量：418.49
纯度：98%
存储：Store at -20°C

Background:

NRC-2694 is an epidermal growth factor receptor (EGFR) antagonist with anti-cancer and anti-proliferative properties.

NRC-2694 at 80 ng (190 nm) concentrations causes comparable inhibition of EGFR expression[1].

In toxicity studies, the maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (po). NRC-2694 (10 mg/kg) regresses the tumor in mice[1].

[1]. Ramanadham Jyothi Prasad, et al. 6-7,dialkoxy quinazoline derivatives useful for treatment of cancer related disorders. US 8143250 B2