(±)-BAY-1251152是BAY-1251152的消旋混合物。BAY-1251152是一种有效且高选择性的PTEF/CDK9抑制剂。
CAS:1610358-53-6
分子式:C19H18F2N4O2S
分子量:404.43
纯度:98%
存储:Store at -20°C
Background:
(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.
[1]. Luecking, et al. Identification of potent and highly selective PTEFb inhibitor BAY 1251152 for the treatment of cancer: from p.o. to i.v. application via scaffold hops [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 984. doi:10.1158/1538-7445.AM2017-984