MI-219 is a human double minute 2 (HDM2) inhibitor. References: Sosin AM, Burger AM, Siddiqi A, Abrams J, Mohammad RM, Al-Katib AM. HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas. J Hematol Oncol. 2012 Sep 18;5:57. doi: 10.1186/1756-8722-5-57. PubMed PMID: 22989009; PubMed Central PMCID: PMC3473265.

纯度：≥98%

CAS：908027-55-4