BACE-IN-1(化合物13)是咪唑[1,2-a]吡啶衍的生物,其可以抑制β位点淀粉样蛋白前体蛋白切割酶(BACE),并且其可用于治疗涉及BACE的疾病,例如阿尔茨海默氏病。
CAS:1254166-60-3
分子式:C22H16ClN5O2
分子量:417.85
纯度:98%
存储:Store at -20°C
Background:
BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer’s disease.
[1]. Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1