Lintopride是5HT4拮抗剂,对5HT3有轻微拮抗作用。
CAS:107429-63-0
分子式:C14H19ClN4O2
分子量:310.78
纯度:98%
存储:Store at -20°C
Background:
Lintopride is a 5HT4 antagonist with moderate 5HT3 antagonist properties.
Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride[1].
[1]. Delvaux M, et al. The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.