Artefenomel (OZ439) 是一种合成的含有青蒿素药效团的抗疟疾药物。Artefenomel (OZ439) 是一种长效青蒿素相关化合物。
CAS:1029939-86-3
分子式:C28H39NO5
分子量:469.61
纯度:98%
存储:Store at -20°C
Background:
Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore. Artefenomel (OZ439) is a long-acting artemisinin-related agent[1].
[1]. Phyo AP, et al. Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial. Lancet Infect Dis. 2016 Jan;16(1):61-69.
[2]. Rosenthal PJ. Artefenomel: a promising new antimalarial drug. Lancet Infect Dis. 2016 Jan;16(1):6-8.