Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH; IC50 = 4.1 μM).
CAS:3158-56-3
分子式:C21H36O2
分子量:320.5
纯度:98%
存储:Store at -20°C
Background:
Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH; IC50 = 4.1 µM). It prevents triglyceride accumulation in 3T3-L1 cells when applied at 5-7.5 µM. Adipostatin A is cytotoxic against fibroblast carcinoma KB cell lines with an IC50 value of 10.6 µM. It also shows larvicidal activity (LC90 = 10.22 ppm) against A. aegypti.