Ribocil-B是ribocil的活性S-异构体,可以抑制黄素单核苷酸(FMN),其KD值为6.6nM。
CAS:1825355-55-2
分子式:C19H22N6OS
分子量:382.48
纯度:98%
存储:Store at -20°C
Background:
Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
Ribocil-B (S-isomer) is a tight binder to the FMN riboswitch and ribocil-A (R-isomer) does not similarly interact and display antibiotic activity[1].
[1]. John A. Howe, et al. Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch.