Methylergonovine Maleate is the maleate salt of methylergonovine, a semi-synthetic ergot alkaloid with vasoconstrictive and uterotonic effects. Methylergonovine stimulates serotoninergic and dopaminergic receptors as well as inhibits the release of endothelial-derived relaxation factor. This results in arterial vasoconstriction and increased uterine smooth muscle contractions. References: Bateman BT, Huybrechts KF, Hernandez-Diaz S, Liu J, Ecker JL, Avorn J.
Methylergonovine maleate and the risk of myocardial ischemia and infarction. Am J
Obstet Gynecol. 2013 Nov;209(5):459.e1-459.e13. doi: 10.1016/j.ajog.2013.07.001.
Epub 2013 Jul 11. PubMed PMID: 23850529; PubMed Central PMCID: PMC4103983.
纯度:≥98%
CAS:57432-61-8