Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces.
CAS：54526-94-2
分子式：C29H32O13
分子量：588.6
纯度：98%
存储：Store at -20°C

Background:

Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine. Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s = 3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC = 5.2 nM), B. cereus (MIC = 1.56 μg/ml), and P. falciparum (IC50 = 2.19 μM).