Citromycetin is a fungal metabolite originally isolated from P.
CAS:478-60-4
分子式:C14H10O7
分子量:290.2
纯度:98%
存储:Store at -20°C
Background:
Citromycetin is a fungal metabolite originally isolated from P. frequentans with antibiotic activity against the Gram-positive bacteria S. aureus and the Gram-negative bacteria V. cholerae and S. flexneri (MICs = 64 µg/ml for both). Citromycetin is selectively cytotoxic to cancerous cells over non-cancerous cells (LC50s = 9.21 and 261.14 µg/ml for HeLa and Vero cells, respectively). Formulations containing citromycetin have been studied for use in the treatment of amyloidosis and α-synuclein fibril diseases.