Heronamide C is a polyketide macrolactam antifungal agent produced by marine Actinomycetes.
CAS：1257083-94-5
分子式：C29H39NO3
分子量：449.6
纯度：98%
存储：Store at -20°C

Background:

Heronamide C is a polyketide macrolactam antifungal agent produced by marine Actinomycetes. It inhibits the growth of and induces abnormal accumulation of cell wall material in wild-type fission yeast cells (MIC = 0.13-0.28 μM). Heronamide C lacks activity against Gram-positive bacteria and human HeLa and MDA-MB-231 cancer cell lines. However, it induces reversible morphological changes, including formation of large intracellular structures, in HeLa cells at a concentration of 20 μM.