Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.
CAS:29557-51-5
分子式:C17H38NO4P
分子量:351.5
纯度:98%
存储:Store at -20°C
Background:
Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR. It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane. Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)). Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.