Statine是一种罕见的氨基酸,在胃蛋白酶抑制剂的序列中出现两次,胃蛋白酶抑制剂是一种对胃蛋白酶和其他酸性蛋白酶有抑制作用的蛋白酶抑制剂。
CAS:49642-07-1
分子式:C8H17NO3
分子量:175.23
纯度:98%
存储:Store at -20°C
Background:
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Statine is also an analog of the previously proposed transition state for catalysis by pepsin and other acid proteases[1].
[1]. Marciniszyn J Jr, et al. Mode of inhibition of acid proteases by pepstatin. J Biol Chem. 1976 Nov 25;251(22):7088-94.