15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α.
CAS:35864-81-4
分子式:C21H36O5
分子量:368.5
纯度:98%
存储:Store at -20°C
Background:
15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α. 15(R)-15-methyl PGF2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.