Fosfructose(Diphosphofructose;Esafosfan;FDP)是一种细胞保护性的天然糖磷酸盐,用于治疗心血管缺血,镰状细胞性贫血和哮喘。它通过刺激无氧糖酵解起作用,其在缺血条件下产生三磷酸腺苷。
CAS:488-69-7
分子式:C6H14O12P2
分子量:340.12
纯度:98%
存储:Store at -20°C
Background:
Fosfructose (Diphosphofructose;Esafosfan;FDP) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.
[1]. Folkesson HG, et al. Fosfructose (Questcor). IDrugs. 2001 Dec;4(12):1401-7.