N-Desmethylclobazam is an analytical reference material that is structurally categorized as a benzodiazepine.
CAS：22316-55-8
分子式：C15H11ClN2O2
分子量：286.7
纯度：98%
存储：Store at -20°C

Background:

N-Desmethylclobazam is an analytical reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam positively modulates GABAA receptors (EC50s range from 98 to 151 uM, depending on subunit configuration). This product is intended for research and forensic applications. This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.