Caspase-3/7 inhibitor
CAS：220509-74-0
分子式：C14H16N2O5S
分子量：324.4
纯度：98%
存储：Store at -20°C

Background:

Caspase-3/7 inbibitor Iis a potent, reversible, isatin sulfonamide-based inhibitor of caspase-3 (KI(app) = 60 nM) and caspase-7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase-9 (Ki(app) = 3.1 mM). It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase-1, caspase-2, caspase-4, caspase-6, and caspase-8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50