5,6-Dihydrouridine是在细菌，真核生物和一些古细菌中的tRNA的D-环中的保守位置中发现的修饰碱基。
CAS：5627-05-4
分子式：C8H13N3O6
分子量：247.21
纯度：98%
存储：Store at -20°C

Background:

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.

5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the "D-loop" of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop[1].

[1]. Kasprzak JM, et al. Molecular evolution of dihydrouridine synthases. BMC Bioinformatics. 2012 Jun 28;13:153.