8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO.
CAS:80234-65-7
分子式:C20H32O4
分子量:336.5
纯度:98%
存储:Store at -20°C
Background:
8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 µM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.