AZD 2066 是一种选择性、可口服、能透过血脑屏障的 mGluR5 拮抗剂,具有镇痛作用。
CAS:934282-55-0
分子式:C19H16ClN5O2
分子量:381.82
纯度:98%
存储:Store at -20°C
Background:
AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].
[1]. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.