MHP is an activator of sphingosine kinase (SPHK1)
CAS：1104874-94-3
分子式：C??H??NO?
分子量：293.36
纯度：98%
存储：Store at -20°C

Background:

MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity[1].

MHP (50-250 μM for 24 hours) increases CAMP mRNA levels in keratinocytes[1].MHP (100 μM for 24 hours) increases CAMP protein levels in keratinocytes[1].

参考文献:
[1]. Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34.