Mequitamium iodide, formerly known as LG-30435, is a platelet activating factor (PAF) inhibitor potentially for the treatment of asthma. LG 30435 inhibits PAF-acether induced platelet aggregation and bronchoconstriction. LG 30435 is capable of inhibiting platelet-mediated effects of PAF by interfering with secondary mechanisms activated by this autacoid and not by direct antagonism of PAF at receptor sites. References: Evangelista S, Boni P, Castellucci A, Perretti F, Pretolani M, Joseph D, Renzetti AR, Subissi A, Manzini S. Antihistaminic and antiallergic properties of dextro-mequitamium iodide in upper and lower guinea pig airways: comparison with azelastine. Gen Pharmacol. 1998 Apr;30(4):513-9. PubMed PMID: 9522168.
纯度:≥98%
CAS:101396-42-3