Tenosal是一种通过将水杨酸与2-噻吩羧酸酯化而得到的新型化合物，具有抗炎，镇痛和退热特性。
CAS：95232-68-1
分子式：C12H8O4S
分子量：248.25
纯度：98%
存储：Store at -20°C

Background:

Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.

Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA[1].

[1]. Lucarelli C, et al. Evaluation of 2-(2-thiophenecarboxy)benzoic acid and related active metabolites in biological samples. J Chromatogr. 1992 Jan 3;573(1):150-3.