CP-319340(free base)

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CAS NO:	186390-35-2
规格:	98%
分子量:	476.49

包装与价格：

包装	价格(元)
1mg	询价
5mg	询价
10mg	询价
20mg	询价

CP-319340freebase是一种微粒体甘油三酯转移蛋白(MTP)抑制剂。
CAS：186390-35-2
分子式：C27H23F3N4O
分子量：476.49
纯度：98%
存储：Store at -20°C

Background:

CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB[3].

[1]. Sugi, Kiyoshi, et al. Process for producing 4-(2-methylphenyl)benzotrifluoride. EP1700837A1. [2]. Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1. [3]. Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44(1):22-32.