Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium).
CAS:73630-23-6
分子式:C26H23N3O10.4K
分子量:693.9
纯度:98%
存储:Store at -20°C
Background:
Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 and 492 nm, respectively.