Glabrene 是一种来源于甘草根的异黄酮,具有雌激素样活性。Glabrene 是 tyrosinase 抑制剂,IC50 值为 3.5 μM。
CAS:60008-03-9
分子式:C20H18O4
分子量:322.35
纯度:98%
存储:Store at -20°C
Background:
Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM[1][2].
IC50: 3.5 μM (Tyrosinase)[2]
[1]. Somjen D, et al. Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):241-6.
[2]. Nerya O, et al. Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem. 2003 Feb 26;51(5):1201-7