Cyclosporin B is a minor cyclopeptide metabolite produced by T.
CAS：63775-95-1
分子式：C61H109N11O12
分子量：1188.6
纯度：98%
存储：Store at -20°C

Background:

Cyclosporin B is a minor cyclopeptide metabolite produced by T. polysporum and other deuteromycota with diverse biological activities. It inhibits the growth of T lymphoma cells in a concentration-dependent manner. It is toxic to mosquito (C. pipiens) larvae (LC50 = 3.0 μg/ml). Cyclosporin B also inhibits P-glycoprotein (P-gp) activity in vitro with an IC50 value of 4.7 μM.