Cyclocreatine is a planar creatine analog that can passively transit across membranes, including the blood brain barrier, and is phosphorylated and dephosphoryated by mitochondrial and cytosolic creatine kinase.
CAS:35404-50-3
分子式:C5H9N3O2
分子量:143.1
纯度:98%
存储:Store at -20°C
Background:
Cyclocreatine is a planar creatine analog that can passively transit across membranes, including the blood brain barrier, and is phosphorylated and dephosphoryated by mitochondrial and cytosolic creatine kinase. Cyclocreatine can function as a phosphagen in mouse brain in vivo and has been used to reverse cognitive deficits in Slc6a8-/y mice that lack a functional creatine transporter.