Cycloguanil 是 Proguanil 的活性代谢产物,作用于红细胞和肝细胞中的疟疾裂殖体。
CAS:516-21-2
分子式:C11H14ClN5
分子量:251.72
纯度:98%
存储:Store at -20°C
Background:
Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
[1]. Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.