Calcineurinsubstrate是来自cAMP依赖性蛋白激酶调节性RII亚基的多肽。它可用于钙调神经磷酸酶活力的测定。
CAS:113873-67-9
分子式:C92H150N28O29
分子量:2112.35
纯度:98%
存储:Store at -20°C
Background:
Calcineurin substrate is a peptide from the regulatory RII subunit of cAMP-dependent protein kinase. It can be used in the calcineurin activity assay.
Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves[1].
[1]. Crabtree GR, et al. Calcium, calcineurin, and the control of transcription. J Biol Chem. 2001 Jan 26;276(4):2313-6.