Benzodiazepine inverse agonist
CAS:1215833-62-7
分子式:C17H18N2O4.HCl
分子量:350.8
纯度:98%
存储:Store at -20°C
Background:
DMCM (hydrochloride) is Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.The reference for administration is ranging 0.4 from 0.8 mg/kg .DMCM (hydrochloride) was shown to bind to GABAA/benzodiazepine receptors in the rat brain with high affinity.DMCM (hydrochloride) can inhibit pain and learning in rats.
参考文献:
[1]. Sieve AN et al. Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacology (Berl), 2001 Jan 1, 153(2):180-90.