Ralfinamide (FCE-26742A) 是一种口服可利用,来源于 α-aminoamide 的钠离子通道阻滞剂, 具有镇痛作用。
CAS:133865-88-0
分子式:C17H19FN2O2
分子量:302.34
纯度:98%
存储:Store at -20°C
Background:
Ralfinamide (FCE-26742A) is an orally available Na(+) channel blocker derived from α-aminoamide, with function of suppressing pain[1].
Sodium Channel[1]
[1]. Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139(2):293-305.
[2]. Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.