G3-C12是galectin-3结合肽，Kd值为88nM，具有抗肿瘤活性。
CAS：848301-94-0
分子式：C74H115N23O23S2
分子量：1758.98
纯度：98%
存储：Store at -20°C

Background:

G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.

G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].

[1]. Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.