CTX1是一种新型小分子p53激活剂。
CAS：501935-96-2
分子式：C14H10N4
分子量：234.26
纯度：98%
存储：Store at -20°C

Background:

CTX1 is a novel small molecule p53 activator.

CTX1 induces significant p53-dependent cell death preferentially in HdmX-expressing cells as compare to cells in which p53 is inactivated by Hdm2 overexpression or p53 is knocked down using p53 targeting shRNA. CTX1 can induce p53 protein levels in the p53 mutant cell line, HT29. It is also found that CTX1 exhibits potent activity (LD50