Rimeporide(EMD-87580)

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	187870-78-6
规格:	98%
分子量:	333.38

包装与价格：

包装	价格(元)
1mg	询价
5mg	询价

Rimeporide(EMD-87580)是一种有效的选择性Na+/H+交换泵(NHE-1)抑制剂。
CAS：187870-78-6
分子式：C11H15N3O5S2
分子量：333.38
纯度：98%
存储：Store at -20°C

Background:

Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].

[1]. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.