Rhod-2AM是一种荧光线粒体探针(λex=552nm，λem=581nm)。
CAS：129787-64-0
分子式：C51H57BrN4O19
分子量：1109.92
纯度：98%
存储：Store at -20°C

Background:

Rhod-2 AM is a fluorescent, mitochondrial probe (λex=552 nm, λem=581 nm).

A high concentration of Ca2+ in mitochondria is illustrated by punctate labeling in cells, which is consistent with the location of Ca2+ in the mitochondria following fluorescence staining with Rhod-2 AM (Rhod2-AM) at 6 h p.i.. Inhibition of mitochondrial Ca2+ uptake by ruthenium red (RR) or 4,4’-diisothiocyanatostilbene-2,2’-disulfonic acid (DIDS) in IMR5 cells infected with poliovirus (PV) is also illustrated following fluorescence staining with Rhod-2 AM at 6 h p.i.[1].

[1]. Brisac C, et al. Calcium flux between the endoplasmic reticulum and mitochondrion contributes to poliovirus-induced apoptosis. J Virol. 2010 Dec;84(23):12226-35.