Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition.
CAS:10141-51-2
分子式:C11H17NO.HCl
分子量:215.8
纯度:98%
存储:Store at -20°C
Background:
Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of δ5/δ6 desaturase. Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 µM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-induced state of essential fatty acid deficiency.