9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp.
CAS:51867-94-8
分子式:C17H25NO4
分子量:307.4
纯度:98%
存储:Store at -20°C
Background:
9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs = 4-20 μg/ml) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC = 0.02 μg/ml for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.