bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.
CAS：65664-81-5
分子式：C32H22N2O6S2.2K
分子量：672.9
纯度：98%
存储：Store at -20°C

Background:

bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation. Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings. bis-ANS has an excitation maxima of 390 nm. It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima of 484-496 nm. bis-ANS has been used to label mechanically damaged neurons in acute brain slices. It also potently inhibits microtubule assembly.