ZED-1227 是一种特异性的、口服的转谷氨酰胺酶 2 (TG2) 抑制剂，能阻塞炎症诱导的 TG2 表达和激活，有作为治疗乳糜泻药物的前景。
CAS：1542132-88-6
分子式：C26H36N6O6
分子量：528.6
纯度：98%
存储：Store at -20°C
Background:
ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1].
TG2[1]
[1]. Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490.
